Collagen Cross-Linking using Riboflavin and UVA exposure

For stabilization of a weakened cornea due to a keratoconus or keratectasia

What is a keratoconus?

A keratoconus is a hereditary corneal disease typically diagnosed during adolescence or early adulthood. It occurs when the normally round dome-shaped cornea progressively thins, causing a cone-like bulge of the cornea to develop. The keratoconus progresses at variable speed and causes a progressing reduced visual acuity that can make simple daily tasks, such as driving, watching television or reading difficult to perform. The incidence of keratokonus in Europe is about 1 : 2000.

So far, treatment methods such as rigid contact lens or intracorneal ring segments aimed only at the correction of the refractive error without any effect on the progression of the disease. It is estimated that eventually about 20% of keratoconus patients require surgical intervention (corneal transplant) to restore corneal anatomy and eyesight.

The actual cause of keratoconus is not yet known, but there have been studies to suggest a genetic and inherited link to the disease.

What is keratectasia?
Why collagen cross-linking?
What happens during the procedure?
What results can be expected?
What are possible complications and side effects?
Treatment costs
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